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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1986 Jul;83(13):4604–4606. doi: 10.1073/pnas.83.13.4604

Phototoxicity of the tetracyclines: photosensitized emission of singlet delta dioxygen.

T Hasan, A U Khan
PMCID: PMC323789  PMID: 3088562

Abstract

The spectroscopic observation of 1268-nm emission of singlet oxygen photosensitized by tetracyclines in oxygenated solutions at room temperature is reported. In the series demeclocycline, tetracycline, and minocycline, the efficiency of singlet oxygen generation is found to parallel the clinical observation of relative frequency of phototoxicity of these antibiotics, suggesting singlet oxygen generation as the origin of their phototoxicity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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