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. Author manuscript; available in PMC: 2012 Dec 7.
Published in final edited form as: Structure. 2011 Dec 7;19(12):1826–1836. doi: 10.1016/j.str.2011.09.018

Figure 4. Caskin1 Self-Association in Living Cells.

Figure 4

(A) CHO-K1 cells co-transfected with mCherry-Caskin1wt and CFP-Caskin1wt fusion proteins both express to the cytoplasm. (B) The cross-correlation profile derived from the auto-correlation function (ACF) profiles of mCherry-Caskin1wt and CFP-Caskin1wt fusion proteins, indicate these species self-associate (blue = ACF of CFP, red = ACF of mCherry, and pink = cross-correlation). (C) The cross-correlation profile derived from the ACF profiles of mCherry-Caskin1mut and CFP-Caskin1mut indicate that these species do not self-associate (colored as in panel B). (D) A bar graph of the diffusion coefficients of the individual and associated species (mean ± std. dev.).