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. 1980 Sep 11;8(17):3743–3755. doi: 10.1093/nar/8.17.3743

Nuclease digestion promotes structural rearrangements in H1-depleted chromatin.

W O Weischet, K E Van Holde
PMCID: PMC324192  PMID: 7443516

Abstract

Digestion of H1-depleted chromatin with micrococcal nuclease at an ionic strength of 0.35M gives rise to structural rearrangements indicating nucleosomal sliding. The ionic strength necessary to reveal this effect is significantly lower than that required in the absence of an accompanying digestion. As an explanation, a model is presented in which the progressing terminal degradation of oligomeric nucleosomes is made responsible for promoting structural rearrangements.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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