Fig. 1.

Spontaneous, oxytocin and high K-induced activity. Spontaneous and oxytocin-induced activity. a and c Simultaneous measurements of force and Ca (Indo-1) in myometrium from non-diabetic (a) and diabetic patients (c) during spontaneous activity. Typical records from 40 diabetic and 68 non-diabetic patients. Effects of 10 nmol/l oxytocin (b and d), typical of at least five other records for both groups. e Comparison of the effects of 40 mmol/l K stimulation after a spontaneous contraction in non-diabetic and diabetic myometrium, typical of 13 others. f and g Representative Indo-1 records showing the Ca signals in response to spontaneous (f) and high K stimulation (g) in samples from non-diabetic and diabetic patients. In this and subsequent samples all data were obtained on myometrium from elective CS biopsies at 35°C and superfused physiological solution containing 8 mmol/l glucose