Table 1.
Values of Model Parameters used in this Study for Mass and Heat Transfer, Permeability & Cytotoxicity. Cell permeability parameters and cytotoxicity parameters were assumed to be the same for both cell types. Water permeability values (Lp) were higher for DMSO than for PD and were used for all simulations.
| Deff/Dbulk | α (μm2/s) | Lp (A) (μm/min atm) | Lp (Ea) (cal/mol) | Ps (A) (μm/s) | Ps (Ea) (cal/mol) | B (mol/kg)−1 | b (L/mol min) | d (K) | f (L/mol) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Alginate | 0.8 | 1.46E11 | -- | -- | -- | -- | -- | -- | -- | -- |
| Cartilage | 0.3 | 1.32E5 | -- | -- | -- | -- | -- | -- | -- | -- |
| Me2SO | -- | -- | 6.67E-4 | 15400 | 4.73E-2 | 14100 | 0.0843 | 2.0E4 | 4270 | 0.08 |
| PD | -- | -- | -- | -- | 5.81E-2 | 14600 | 0.0576 | 1.2E5 | 4930 | 0.17 |