Abstract
In 1929 Charles Lindbergh became interested in the development of a heart-bypass pump to enable open-heart surgery, and was introduced to Alexis Carrel. Carrel persuaded Lindbergh to work instead on a perfusion system for the culture of whole organs outside the body, and by 1934—when I met Lindbergh in Copenhagen—he already had developed a pump with floating glass valves that allowed precise regulation of perfusion pressure and rate. I joined Lindbergh and Carrel at the Rockefeller Institute to work on organ culture, using the pump. My subsequent contact with Lindbergh came at Columbia, where I experimented with hemocyanin as a blood substitute, and (much later) at Huntington Medical Research Institutes, where I found his pump useful in the study of cholesterol uptake by arteries. (Texas Heart Institute Journal 1987; 14:231-237)
Keywords: History of medicine, 20th century
Keywords: historical biography/Carrel/Lindbergh/Bing
Keywords: perfusion
Keywords: organ culture
Keywords: organ preservation
Keywords: surgical equipment/history
Keywords: cardiopulmonary bypass
Keywords: extracorporeal circulation
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These references are in PubMed. This may not be the complete list of references from this article.
- Cooley D. A. Development of the roller pump for use in the cardiopulmonary bypass circuit. Tex Heart Inst J. 1987 Jun;14(2):112–118. [PMC free article] [PubMed] [Google Scholar]