Abstract
The time to systolic murmur peak is a clinical index that is useful in assessing the severity of valvular aortic stenosis. To determine whether phonocardiography could be used to detect a change in the timing of the murmur and thus to measure hemodynamic improvements in elderly balloon aortic valvuloplasty patients, we retrospectively reviewed phonocardiographic tracings of 18 patients taken before and after the procedure. Ten men and 8 women were included in the study; the mean age was 80.7 ± 11.2 years (range, 64 to 90). Phonocardiographic signals were digitized, and the R-wave to murmur peak interval (R-MP) was measured. In 11 patients, the R-MP decreased (mean decrease, 16% ± 11%): of these, 10 had a significant (> 25%) decrease in mean gradient; 10 had a significant (> 25%) decrease in peak-to-peak gradient; and the average increase in aortic valve area was 38%. Seven patients had an increase in R-MP (mean increase, 10% ± 9%): of these, 6 had a decrease in mean gradient of less than 25%; 6 had a decrease in peak-to-peak gradient of less than 25%; and the average increase in aortic valve area was 21%. Pre- and post-balloon aortic valvuloplasty heart rates were not significantly different (71 ± 8 beats/min versus 73 ± 5 beats/min). In this study, hemodynamic improvements after valvuloplasty were manifested by a reduction in the R-MP interval. We conclude that phonocardiography may be a practical, noninvasive method of assessing the hemodynamic response to balloon aortic valvuloplasty. (Texas Heart Institute Journal 1990;17:42-7)
Keywords: Aortic stenosis
Keywords: hemodynamics
Keywords: phonocardiogram
Keywords: systolic ejection murmur
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Selected References
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- Bonner A. J., Jr, Sacks H. N., Tavel M. E. Assessing the severity of aortic stenosis by phonocardiography and external carotid pulse recordings. Circulation. 1973 Aug;48(2):247–252. doi: 10.1161/01.cir.48.2.247. [DOI] [PubMed] [Google Scholar]
- Come P. C., Riley M. F., McKay R. G., Safian R. Echocardiographic assessment of aortic valve area in elderly patients with aortic stenosis and of changes in valve area after percutaneous balloon valvuloplasty. J Am Coll Cardiol. 1987 Jul;10(1):115–124. doi: 10.1016/s0735-1097(87)80169-9. [DOI] [PubMed] [Google Scholar]
- Cribier A., Savin T., Saoudi N., Rocha P., Berland J., Letac B. Percutaneous transluminal valvuloplasty of acquired aortic stenosis in elderly patients: an alternative to valve replacement? Lancet. 1986 Jan 11;1(8472):63–67. doi: 10.1016/s0140-6736(86)90716-6. [DOI] [PubMed] [Google Scholar]
- GORLIN R., GORLIN S. G. Hydraulic formula for calculation of the area of the stenotic mitral valve, other cardiac valves, and central circulatory shunts. I. Am Heart J. 1951 Jan;41(1):1–29. doi: 10.1016/0002-8703(51)90002-6. [DOI] [PubMed] [Google Scholar]
- Nishimura R. A., Holmes D. R., Jr, Reeder G. S., Orszulak T. A., Bresnahan J. F., Ilstrup D. M., Tajik A. J. Doppler evaluation of results of percutaneous aortic balloon valvuloplasty in calcific aortic stenosis. Circulation. 1988 Oct;78(4):791–799. doi: 10.1161/01.cir.78.4.791. [DOI] [PubMed] [Google Scholar]
- Nitta M., Nakamura T., Hultgren H. N., Bilisoly J., Marquess B. Noninvasive evaluation of the severity of aortic stenosis in adults. Chest. 1987 May;91(5):682–687. doi: 10.1378/chest.91.5.682. [DOI] [PubMed] [Google Scholar]
- Nitta M., Nakamura T., Hultgren H. N., Bilisoly J., Tovey D. A. Progression of aortic stenosis in adult men. Detection by noninvasive methods. Chest. 1987 Jul;92(1):40–43. doi: 10.1378/chest.92.1.40. [DOI] [PubMed] [Google Scholar]
- Oakley C. M., Hallidie-Smith K. A. Assessment of site and severity in congenital aortic stenosis. Br Heart J. 1967 May;29(3):367–379. doi: 10.1136/hrt.29.3.367. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Voelkel A. G., Kendrick M., Pietro D. A., Parisi A. F., Voelkel V., Greenfield D., Askenazi J., Folland E. D. Noninvasive tests to evaluate the severity of aortic stenosis. Limitations and reliability. Chest. 1980 Feb;77(2):155–160. doi: 10.1378/chest.77.2.155. [DOI] [PubMed] [Google Scholar]
