Table 1.
Control | DM | DM + TOP | |
---|---|---|---|
Body weight (g) | 39.0 ± 3.3 | 31.6 ± 2.2b | 29.4 ± 3.3b |
Blood glucose (mg/dl) | 165 ± 53.3 | >250a | >250a |
Na (mmol/liter) | 149 ± 2.1 | 142 ± 4.1a | 143 ± 4.4a |
K (mmol/liter) | 8.1 ± 0.9 | 6.1 ± 2.6a | 7.1 ± 1.1 |
Cl (mmol/liter) | 121 ± 2.3 | 111 ± 3.0a | 112 ± 4.4a |
Ca+2 (mmol/liter) | 1.24 ± 0.1 | 1.23 ± 0.1 | 1.26 ± 0.1 |
TCO2 (mmol/liter) | 15 ± 2.6 | 18 ± 3.4 | 16 ± 5.0 |
BUN (mg/dl) | 21 ± 2.8 | 22 ± 7.6 | 24 ± 4.5 |
Creatinine (mg/dl) | 0.21 ± 0.03 | 0.20 ± 0.00 | 0.20 ± 0.00 |
Hematocrit (% PCV) | 43 ± 3.0 | 46 ± 3.3 | 46 ± 2.2 |
Hemoglobin (g/dl) | 14.7 ± 1.0 | 15.7 ± 1.1 | 15.5 ± 0.8 |
AnGap (mmol/liter) | 20.6 ± 2.5 | 19.3 ± 4.4 | 22.9 ± 4.5 |
Values are mean ± sem, n = 10.
P < 0.05 for difference from controls.
P < 0.0001 for difference from controls. PCV, Packed cell volume; AnGap, anion gap.