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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 2011 Dec 12;108(51):20850. doi: 10.1073/pnas.1118432108

Retraction for Dougan et al., Probing osmolyte participation in the unfolding transition state of a protein

PMCID: PMC3251118  PMID: 22160710

CHEMISTRY Retraction for “Probing osmolyte participation in the unfolding transition state of a protein,” by Lorna Dougan, Georgi Z. Genchev, Hui Lu, and Julio M. Fernandez, which appeared in issue 24, June 14, 2011, of Proc Natl Acad Sci USA (108:9759–9764; first published May 25, 2011; 10.1073/pnas.1101934108).

The authors note the following: “We wish to retract our article because interpretation of the experimental data was based on incorrect calibration of the apparatus in viscous solutions and there is no basis for the major conclusions of the study on the structure of the transition state for mechanical unfolding.”


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