Table 5.
Infarct number and region and cognitive performancea
| Parameter estimate for cognitive domain scores, standard errors (p value) |
|||||||
|---|---|---|---|---|---|---|---|
| n in each category | global cognition | episodic memory | semantic memory | working memory | perceptual speed | visuospatial ability | |
| No infarct | 424 | reference | reference | reference | reference | reference | reference |
| One infarct/one region | 108 | 0.044, 0.047 (0.357) | 0.104,0.060 (0.083) | 0.041,0.059 (0.494) | −0.019,0.063 (0.768) | −0.041,0.075 (0.586) | −0.051,0.064 (0.422) |
| Two or more/single region | 34 | −0.157,0.079 (0.047) | −0.194,0.099 (0.051) | −0.105,0.099 (0.288) | −0.152,0.105 (0.150) | −0.284,0.125 (0.023) | −0.170,0.107 (0.112) |
| Two or more/multiple regions | 14 | −0.364,0.123 (0.003) | −0.353,0.155 (0.024) | −0.362,0.153 (0.018) | −0.336,0.165 (0.041) | −0.590,0.188 (0.002) | −0.005,0.165 (0.975) |
a
Linear regression models controlling for age, sex, education, race, and elapsed time from clinical evaluation to MRI.