Table 1:
Characteristic | No. (%) of individuals* | ||
---|---|---|---|
Matched controls n = 36 034 |
Patients with chronic kidney disease n = 6 320 |
Patients receiving hemodialysis n = 36 474 |
|
Age, yr, mean (SD) | 63.1 (13.9) | 61.6 (14.2)† | 63.2 (13.8) |
Male sex | 17 525 (48.6) | 3 501 (55.4)† | 17 675 (48.5) |
Hypertension | 11 601 (32.2) | 3 843 (60.8)† | 31 216 (85.6)‡ |
Diabetes | 3 915 (10.9) | 4 255 (67.3)† | 18 796 (51.5)‡ |
Coronary artery disease | 5 151 (14.3) | 1 618 (25.6)† | 12 527 (34.4)‡ |
Heart failure | 1 046 (2.9) | 432 (6.8)† | 9 111 (25.0)‡ |
Cirrhosis | 277 (0.8) | 96 (1.5)† | 1 472 (4.0)‡ |
Medication use | |||
ASA | 5 892 (16.4) | 1 567 (24.8)† | 6 089 (16.7) |
NSAID | 3 064 (8.5) | 980 (15.5)† | 3 144 (8.6) |
Steroid | 1 676 (4.6) | 195 (3.1)† | 1 750 (4.8) |
Clopidogrel | 1 134 (3.2) | 101 (1.6)† | 1 493 (4.1)‡ |
Ticlopidine | 361 (1.0) | 67 (1.1) | 411 (1.1) |
Warfarin | 198 (0.6) | 50 (0.8) | 238 (0.6) |
Ulcer bleeding | 480 (1.3) | 163 (2.6)† | 2 361 (6.5)‡ |
All-cause mortality | 2 831 (7.9) | 915 (14.5)† | 10 329 (28.3)‡ |
Note: ASA = acetylsalicylic acid, NSAID = nonsteroidal anti-inflammatory drug, SD = standard deviation.
Unless stated otherwise.
p < 0.05 for comparison between patients with chronic kidney disease and controls.
p < 0.05 for comparison between patients receiving hemodialysis and controls.