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. 2011 Dec 1;6(12):1413–1424. doi: 10.4161/epi.6.12.18271

Figure 1.

Figure 1

(A) Scheme of the genes and CpG islands organized according to their physical location on 3p21.3 (UCSC Genome Browser on Human, assembly GRCh37/hg19, http://genome.ucsc.edu). (B) Differential gene expression among breast cancer cell lines and non-tumorigenic breast cells. The HYAL2, TUSC2 and CACNA2D2 genes were differentially expressed in breast cancer compared with non-tumorigenic cell lines. Global RASSF1 transcripts showed a trend to overexpression in breast cancer cells lines compared with non-tumorigenic epithelial breast cells 184A1. All quantifications were performed by real-time PCR using specific hydrolysis probes for each target gene normalized to the endogenous control expression levels (GAPDH gene).