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. 2011 Dec;13(12):1101–1112. doi: 10.1593/neo.111060

Figure 2.

Figure 2

Knockdown PAK2 suppresses Wnt/β-catenin signaling. Schwannoma cells were infected with shRNA encoding a sequence targeting human PAK2 (sh-PAK2a) or a matched scramble sequence (Control). Western blot analyses were carried out to compare the levels of pJNK, ABC, c-myc, cyclin D1, and β-catenin between sh-PAK2a and control. Densities of bands were quantified and compared. Error bars represent the mean ± SEM. n = 3. *P < .05. **P < .01. ns indicates no significant difference. pJNK, ABC, c-myc, and cyclin D1 were significantly reduced after knocking down PAK2.