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. 1983 Feb 11;11(3):737–751. doi: 10.1093/nar/11.3.737

Association of a Drosophila transposable element of the roo family with chromosomal deletion breakpoints.

W McGinnis, S K Beckendorf
PMCID: PMC325750  PMID: 6300765

Abstract

A 9.3 kb transposable element of the roo family has been found inserted 3' to the Sgs-4 glue protein gene of Drosophila. The X chromosome which carries this insert also carries wDZL, a dominant, unstable allele of the white locus caused by the insertion of the 13 kb wDZL element. Three deletions isolated from the wDZL strain have molecular breakpoints 3' to Sgs-4 that are associated with the roo element. Though the deletions eliminate much of the DNA between white and Sgs-4, none of the distal breakpoints fall at or near the wDZL element. The results suggest that this copia-like element, which is structurally similar to an integrated retrovirus, is capable of promoting chromosomal deletions.

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Selected References

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