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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Biomaterials. 2011 Dec 17;33(7):2361–2371. doi: 10.1016/j.biomaterials.2011.11.080

Figure 2.

Figure 2

Physicochemical characterization of DNA nanoparticles formulated at pH 7.5. Transmission electron microscopy of compacted DNA nanoparticles formulated with (A) PEG-CK30 and (B) PEG-CH12K18. Scale bar represents 200nm. Colloidal stability of compacted DNA nanoparticles after storage at 4°C for 6 months. (C) Turbidity parameters, an indicator of colloidal stability, for various DNA nanoparticle formulations. A turbidity parameter less than −3.5 (above the dashed line) indicates DNA nanoparticles that are compacted and non-aggregated, whereas values greater than −3.5 (below the dashed line) indicate significant aggregation of DNA nanoparticles. (D) Non-aggregated fraction of compacted DNA nanoparticles as determined by sedimentation. Data represents the mean +/− SD. * denotes statistical significance (** P < 0.01, Tukey HSD).