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. 1983 Jul 11;11(13):4569–4582. doi: 10.1093/nar/11.13.4569

Conformational analysis of the trinucleoside diphosphate 3'd(A2'-5'A2'-5'A). An NMR and CD study.

J Doornbos, R Charubala, W Pfleiderer, C Altona
PMCID: PMC326065  PMID: 6866773

Abstract

A 500 MHz and 300 MHz NMR study of the trinucleoside diphosphate 3'd(A2'-5'A2'-5'A) is presented. In addition, circular dichroism is used to study base stacking in the title compound. The complete 1H-NMR spectral assignment of the sugar ring proton signals is given. Information about the sugar ring (N- or S-type conformation) and about the backbone geometry along C4'-C5' and C5'-O5' bonds is obtained from the NMR coupling constants. It is shown that the trimer mainly occurs in the N-N-N stacked state at low temperatures; the presence of a minor amount of N-N-S conformational sequence is indicated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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