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. 1983 Jul 11;11(13):4655–4663. doi: 10.1093/nar/11.13.4655

Calculating the expected frequencies of potential secondary structure in nucleic acids as a function of stem length, loop size, base composition and nearest-neighbor frequencies.

W M Fitch
PMCID: PMC326072  PMID: 6306598

Abstract

A formula is derived to estimate the expected frequency of potential secondary structure of a given stem length and loop size in a random sequence of nucleotides of known length and composition. An example is provided using the SV40 sequence which shows significant non-randomness in stem length but whose significance is reduced by more than six orders of magnitude by taking nearest neighbor frequencies into account.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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