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. 1982 Jan 22;10(2):565–576. doi: 10.1093/nar/10.2.565

Tissue specificity and organisation of CpG methylation in calf satellite DNA I.

M Pages, G Roizes
PMCID: PMC326158  PMID: 6278421

Abstract

Examination of bovine satellite DNA I methylation within CpG dinucleotides has been made by restriction analysis. It is shown that variations in the methylation patterns occur between different tissues (brain, liver, thymus and sperm) . Some of the 8 Hpa II sites present per repeat are clearly undermethylated in sperm as compared to other tissues. Methylation is considered therefore, as a highly specific event. It is also shown that there is a spatial specificity in the methylation pattern of the 3 Hha I sites in all tissues. These results are discussed in the light of methylation and satellite DNA functions.

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Selected References

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