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. 1983 Aug 11;11(15):5267–5275. doi: 10.1093/nar/11.15.5267

The N-ras oncogene assigned to the short arm of human chromosome 1.

B de Martinville, J M Cunningham, M J Murray, U Francke
PMCID: PMC326261  PMID: 6576326

Abstract

The human N-ras oncogene, isolated from the HL-60 promyelocytic leukemia cell line, is distantly related to viral oncogenes of Kirsten and Harvey sarcoma viruses. We have determined its chromosomal location by Southern blot analysis of DNAs from 37 human x rodent hybrid cell lines derived from 8 different human donors, some of whom carried balanced rearrangements of chromosome 1. The results indicate that the N-ras oncogene (RASN) is localized on the proximal part of the short arm of human chromosome 1, in region p3200 leads to cen.

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Selected References

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