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. 1983 Aug 25;11(16):5475–5482. doi: 10.1093/nar/11.16.5475

Interdigitated arrangement of two oligo(A)-terminated DNA sequences in Drosophila.

P P Di Nocera, I B Dawid
PMCID: PMC326292  PMID: 6310501

Abstract

A cluster of repeated sequences composed of three distinguishable units has been isolated from Drosophila melanogaster, and characterized. The region, cloned as pDmI 158, contains a segment that is homologous to the type 1 ribosomal insertions, a member of the F family of transposable sequences, and a newly described repeated sequence that we have named G. F elements are transposable sequences that lack terminal repeats, generate target site duplications at the point of insertion, and contain an oligo(A) stretch at one end. G sequences are structurally similar though non-homologous to F in that they also carry an oligo(A) stretch. The structure of the 158 region of the genome is best explained by assuming three consecutive events. An F element did insert into a ribosomal insertion-like sequence, followed by the introduction of a G sequence into F. Subsequently, a DNA segment comprising a portion of G and F was tandemly triplicated to yield the arrangement observed. The nested interspersion of repeated sequence elements may be a common feature of eukaryotic genomes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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