Abstract
Sterically hindered N6-dialkylformamidine protected deoxyadenosine is more stable to acidic depurination than N6-benzoyldeoxyadenosine and is potentially a valuable protecting group in the synthesis of deoxyoligonucleotides.
Full text
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chow F., Kempe T., Palm G. Synthesis of oligodeoxyribonucleotides on silica gel support. Nucleic Acids Res. 1981 Jun 25;9(12):2807–2817. doi: 10.1093/nar/9.12.2807. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Letsinger R. L., Miller P. S., Grams G. W. Selective N-debenzoylation of N,O-polybenzoylucleosides. Tetrahedron Lett. 1968 Apr;(22):2621–2624. doi: 10.1016/s0040-4039(00)89658-6. [DOI] [PubMed] [Google Scholar]
- Tanaka T., Letsinger R. L. Syringe method for stepwise chemical synthesis of oligonucleotides. Nucleic Acids Res. 1982 May 25;10(10):3249–3260. doi: 10.1093/nar/10.10.3249. [DOI] [PMC free article] [PubMed] [Google Scholar]