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. Author manuscript; available in PMC: 2012 Dec 28.
Published in final edited form as: Oncogene. 2011 Oct 17;31(26):3164–3176. doi: 10.1038/onc.2011.480

Figure 6. NF-κB activation in IKTA transgenic mice increases the numbers of CD4+CD25+Foxp3+ regulatory T cells in the lungs.

Figure 6

A) Representative flow cytometry plots for identification of CD4+ T cells, CD8+ T cells, and CD4+CD25+Foxp3 Tregs in lungs of WT and IKTA mice treated with doxycycline (dox) for 3 weeks. B) Total CD4+ T cells, CD8+ T cells, and CD4+CD25+Foxp3 Tregs identified by flow cytometry in lungs from untreated WT mice and IKTA mice 1–6 weeks after initiation of dox treatment (n≥4 per group for each time interval, *=p<0.01). C) Relative mRNA expression of CCL17, CCL20 and CCL22 in lung homogenates prepared from WT and IKTA mice after 6 weeks of dox treatment (n=7 for IKTA and 10 for WT, *=p<0.01).