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. 1981 Apr 24;9(8):1963–1971. doi: 10.1093/nar/9.8.1963

Periodicity in DNA primary structure is defined by secondary structure of the coded protein.

V B Zhurkin
PMCID: PMC326816  PMID: 7243595

Abstract

A 10.5-base periodicity found earlier is inherent in both eu- and prokaryotic coding nucleotide sequences. In the case of noncoding eukaryotic sequences no periodicity is found, so the 10.5-base oscillation seemingly does not correlate with the nucleosomal organization of DNA. It is shown that the DNA fragments, coding the alpha-helical protein segments, manifest the pronounced 10.5-base periodicity, while those regions of DNA which code the beta-structure have a 6-base oscillation. The repeating pattern of nucleotide sequences can be used for comparison of the DNA segments with low degree of homology.

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1963

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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