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. 2012 Feb;62(595):68. doi: 10.3399/bjgp12X625049

A systematic review: the role of spirituality in reducing depression in people living with HIV/AIDS

Roxanna Amuzie 1,2, Melvyn Jones 1,2
PMCID: PMC3268470  PMID: 22520767

Vermandere et al's1 article highlighted end-of-life care as a particular area where spirituality can play an important role. In a link between spirituality and another chronic disease we looked at spirituality and HIV (R Amuzie, unpublished data, 2009). Vermandere's literature review proposes that spirituality has a key position in the management of HIV sufferers. HIV infection is a major global problem and in 2007 was present in 33?million people around the world.2 Antiretroviral therapy has been successful in slowing the progression of HIV infection and reducing AIDS-related mortality. But by doing so, HIV infection is now widely considered as a chronic illness and therefore HIV sufferers are beleaguered by similar challenges as those living with chronic illnesses like epilepsy and diabetes mellitus. Research suggests that people with HIV/AIDS are at greater risk of depression,3 and that depression in HIV sufferers is linked with more rapid loss of immune function, accelerated disease progression, and lower survival time.4

In clinical research, spirituality has been broadly defined as a belief in a higher power than oneself that is not thought to be God. Another definition is that spirituality is similar to an individuals' experience of meaning and life purpose.5 It has been reported to reduce the risk of depression in people living with chronic illness. This review was conducted to examine the possible benefits and impact of spirituality on depressive symptoms in people with HIV/AIDS.

Systematic literature searches of PubMed, PsycInfo, and Embase were carried out, along with backwards and forwards citation tracking of key studies, identified 21 qualitative studies, of which five studies610 met the predetermined criteria for eligibility and were included in the review. Formal meta-analysis was not possible due to the nature of the studies.

This review found that a large number of people with HIV/AIDS report experiencing depressive symptoms that are suggestive of mild-moderate depression. Studies provide statistical evidence that a greater level of spirituality in a person with HIV/AIDS is linked to fewer symptoms of depression. However, further research is required to examine the association between spirituality and clinically-diagnosed depression, as well as the impact of spirituality-focused interventions in reducing depression in people with HIV infection or AIDS.

This study was a dissertation undertaken as part of the UCL intercalated BSc in Primary Health Care. R Amuzie. The role of spirituality in reducing depression in men and women living with HIV/AIDS. UCL iBSc dissertation 2009.

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