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. 1982 Oct 25;10(20):6265–6271. doi: 10.1093/nar/10.20.6265

Synthesis and physical characterization of the self-complementary, alternating pyrimidine/purine hexanucleotide d[CGTACG].

S Kuzmich, L A Marky, R A Jones
PMCID: PMC326916  PMID: 7177847

Abstract

The hexanucleotide d(CGTACG) has been synthesized by a phosphotriester method in which, for the first time, an O-6 protected deoxyguanosine derivative has been used to avoid side reactions of the guanine residues. Conformational analysis by circular dichroism shows that d(CGTACG) maintains a B form under conditions (5 M NaCl) where the all C/G hexanucleotide d(CG)3 adopts a Z form, even though d(CGTACG) is a fully alternating pyrimidine/purine molecular. The delta H for the helix-to-coil transition has been measured.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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