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. 1981 Sep 11;9(17):4213–4224. doi: 10.1093/nar/9.17.4213

Highly variable regions of DNA flank the human alpha globin genes.

D R Higgs, S E Goodbourn, J S Wainscoat, J B Clegg, D J Weatherall
PMCID: PMC327430  PMID: 6272199

Abstract

A series of restriction fragment length polymorphisms which are due to DNA rearrangements have been identified within two highly variable regions flanking the human alpha globin genes. The existence of such highly polymorphic areas provides a large number of individual genetic markers for the alpha globin gene cluster on chromosome 16. If, as seems likely, such regions occur frequently throughout the human genome they should be of considerable value in the antenatal diagnosis of genetic disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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