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. 2012 Mar 1;139(5):991–1000. doi: 10.1242/dev.077255

Fig. 8.

Fig. 8.

Model comparing normal and ectopic eye development. In this model, the first step in ectopic eye development is the repression of the antennal/head capsule specifying gene ct. In normal eye development, this is achieved through interactions between the SIX proteins So and Optix with co-repressors. In the second step, Ey activates the entire retinal determination network through So-Eya and Optix-Eya complexes. These two steps then lead to the promotion of eye development.