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. 1981 Sep 25;9(18):4745–4753. doi: 10.1093/nar/9.18.4745

Homologous 3'-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei.

H K Majumder, J C Boothroyd, H Weber
PMCID: PMC327472  PMID: 6170939

Abstract

Sequences corresponding to the complete 3'-terminal regions of the messenger RNAs for three different Variant Surface Glycoproteins of Trypanosoma brucei were determined on complementary DNA inserts cloned in recombinant plasmids. The three sequences show 80-130 base pair long segments of strong (70-80%) homology at the 3' ends, whereas ther regions upstream from the last 130-140 base pairs contain no significant homology. The signal AAUAAA, present near the 3' ends of almost all known polyadenylated mRNAs of eukaryotes, does not occur in the 3'-terminal sequences of these three variants.

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Selected References

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