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. 1981 Oct 10;9(19):4981–4995. doi: 10.1093/nar/9.19.4981

The endogenous proviral mouse mammary tumor virus genes of the GR mouse are not identical and only one corresponds to the exogenous virus.

P Herrlich, N E Hynes, H Ponta, U Rahmsdorf, N Kennedy, B Groner
PMCID: PMC327493  PMID: 6273791

Abstract

The endogenous proviral copies of mouse mammary tumor virus (MMTV) were selected from a gene library of GR mouse DNA. We obtained five different lambda. MMTV recombinant clones. Four of them correspond to the 3' Eco RI fragments of the endogenous proviruses an one comprises an intact MMTV provirus with 2 to 3 kb of flanking mouse genomic DNA. Heteroduplex formation followed by S1 digestion under stringent conditions shows that there is nucleotide sequence heterology among the cloned endogenous proviral copies. Only one endogenous proviral copy, associated with the mtv-2 locus, was found to be totally homologous to the exogenous proviral DNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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