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. 1981 Dec 11;9(23):6591–6599. doi: 10.1093/nar/9.23.6591

Some characteristics of apurinic sites in single- and double-stranded biologically active phi X174 DNA.

M V Lafleur, J Woldhuis, H Loman
PMCID: PMC327624  PMID: 6459567

Abstract

With biologically active DNA of the bacteriophage phi X174, both single and double-stranded, some physico-chemical and biological parameters of the depurination reaction are studied. It is shown that in single-stranded DNA each apurinic site is lethal, while in double-stranded RFI-DNA only about 5% of these sites are lethal. Furthermore it is concluded that the apurinic sites are formed at different rates in single- and double-stranded DNA and also the conversion into breaks of the apurinic sites is different for both forms of DNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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