Table IV.
Distribution of TLV in normal epithelial cells by clinical characteristics in all subjects
| TLV in ANECa |
TLV in DNECb |
|||
| N | Mean (SD) | N | Mean (SD) | |
| Race | ||||
| Whites | 55 | 71.7 (21.6) | 70 | 76.0 (27.0) |
| Blacks | 14 | 65.1 (12.8) | 21 | 62.5 (15.2) |
| Others | 19 | 62.9 (20.2) | 23 | 70.7 (18.9) |
| P value | 0.28 | 0.13 | ||
| Age at diagnosis | ||||
| ≤40 | 19 | 61.6 (15.3) | 20 | 74.2 (30.1) |
| 41–50 | 29 | 72.3 (22.2) | 39 | 69.8 (17.3) |
| 51–60 | 25 | 66.2 (19.9) | 30 | 68.3 (19.4) |
| ≥61 | 15 | 75.0 (21.6) | 25 | 80.0 (31.6) |
| P value | 0.12 | 0.48 | ||
| Stage | ||||
| 0–I | 31 | 71.9 (22.8) | 48 | 76.6 (26.3) |
| II | 47 | 67.8 (19.7) | 55 | 70.3 (22.7) |
| III–IV | 7 | 66.9 (16.5) | 5 | 62.8 (29.1) |
| P value | 0.80 | 0.39 | ||
| Tumor size | ||||
| <1.5 cM | 21 | 81.9 (22.4) | 28 | 82.1 (31.5) |
| ≥1.5 cM | 43 | 66.2 (20.0) | 45 | 71.1 (21.3) |
| P value | 0.003 | 0.12 | ||
| ER status | ||||
| Negative | 21 | 60.5 (19.4) | 21 | 64.0 (18.6) |
| Positive | 33 | 69.5 (20.8) | 43 | 72.8 (23.8) |
| P value | 0.12 | 0.21 | ||
| Histological type | ||||
| Ductal | 72 | 69.1 (21.3) | 94 | 71.0 (21.9) |
| Lobular | 5 | 61.8 (21.0) | 6 | 88.5 (53.3) |
| Ductal and lobular | 5 | 72.0 (11.7) | 6 | 85.3 (23.2) |
| Others | 6 | 67.8 (15.1) | 8 | 67.5 (14.5) |
| P value | 0.69 | 0.49 | ||
P-values were based on Kruskal–Wallis test.
a
Normal-appearing epithelial cells on the same blocks as the tumor cells.
b
Normal-appearing epithelial cells on the separate blocks from the tumor cells.