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. 1981 Dec 21;9(24):6813–6825. doi: 10.1093/nar/9.24.6813

Restriction mapping of a new deletion responsible for Gγ(δβ)o thalassaemia

RW Jones 1, JM Old 1, RJ Trent 1, JB Clegg 1, DJ Weatherall 1
PMCID: PMC327644  PMID: 6278449

Abstract

DNA from individuals heterozygous for Gγ(δβ)o thalassaemia has been studied by restriction endonuclease analysis. The results reveal a new molecular defect associated with this condition. A total of three defects is now responsible for the one single phenotype, thereby emphasising the complex relationship between genotype and phenotype among the disorders of β-like globin synthesis in man.

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Selected References

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