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. 2012 Feb;190(2):295–304. doi: 10.1534/genetics.111.134668

Table 2. Estimates of the rate of change of fitness per generation in nematodes and Drosophila under whole-genome mutation accumulation (ΔMA) and predicted rates of fitness loss per generation for humans (ΔR), if selection is completely relaxed, calculated using Equation 5.

Species No. MA experiments Mean ΔMA under MA U Predicted ΔR in humans
Nematodes 7 0.15% 2.5 0.13%
Drosophila 6 1.2% 1.4 1.8%