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. 1979 Jan;6(1):205–218. doi: 10.1093/nar/6.1.205

Cell specific antiserum to chromosome scaffold proteins.

A M Campbell, R C Briggs, R E Bird, L S Hnilica
PMCID: PMC327683  PMID: 424289

Abstract

Antiserum has been raised to a chromosomal protein fraction specific for Hela cells. The immunoactivity is located in the transcriptionally inactive regions of log phase chromatin. Digestion of metaphase chromosomes results in the purification of the immunoactivity in the scaffold region of the chromosomes. Extensive nuclease digestion of the scaffolds results in loss of activity. The data suggest that some of the proteins in the scaffold area are both tight binding and cell specific and may therefore play a sophisticated role in gene expression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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