Abstract
The nucleotide sequence of Drosophila melanogaster methionine tRNAi was determined to be: pA-G-C-A-G-A-G-U-m1G-m2G-C-G-C-A-G-U-G-G-A-A-G-C-G-U-m2G-C-U-G-G-G-C-C-C-A-U-t6A-A-C-C-C-A-G-A-G-m7G-D-m5C-C-C-G-A-G-G-A-U-C-G-m1A-A-A-C-C-U-U-G-C-U-C-U-G-C-U-A-C-C-A(OH). It differs from vertebrate initiator tRNAs in only 6 out of 75 positions.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Dube S. K., Marcker K. A., Clark B. F., Cory S. Nucleotide sequence of N-formyl-methionyl-transfer RNA. Nature. 1968 Apr 20;218(5138):232–233. doi: 10.1038/218232a0. [DOI] [PubMed] [Google Scholar]
- Gauss D. H., Grüter F., Sprinzl M. Compilation of tRNA sequences. Nucleic Acids Res. 1979 Jan;6(1):r1–r19. [PMC free article] [PubMed] [Google Scholar]
- Gillum A. M., Hecker L. I., Silberklang M., Schwartzbach S. D., RajBhandary U. L., Barnett W. E. Nucleotide sequence of Neurospora crassa cytoplasmic initiator tRNA. Nucleic Acids Res. 1977 Dec;4(12):4109–4131. doi: 10.1093/nar/4.12.4109. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gillum A. M., Urquhart N., Smith M., RajBhandary U. L. Nucleotide sequence of salmon testes and salmon liver cytoplasmic initiator tRNA. Cell. 1975 Nov;6(3):395–405. doi: 10.1016/0092-8674(75)90189-0. [DOI] [PubMed] [Google Scholar]
- Heckman J. E., Hecker L. I., Schwartzbach S. D., Barnett W. E., Baumstark B., RajBhandary U. L. Structure and function of initiator methionine tRNA from the mitochondria of Neurospora crassa. Cell. 1978 Jan;13(1):83–95. doi: 10.1016/0092-8674(78)90140-x. [DOI] [PubMed] [Google Scholar]
- Holmes W. M., Hurd R. E., Reid B. R., Rimerman R. A., Hatfield G. W. Separation of transfer ribonucleic acid by sepharose chromatography using reverse salt gradients. Proc Natl Acad Sci U S A. 1975 Mar;72(3):1068–1071. doi: 10.1073/pnas.72.3.1068. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rich A., RajBhandary U. L. Transfer RNA: molecular structure, sequence, and properties. Annu Rev Biochem. 1976;45:805–860. doi: 10.1146/annurev.bi.45.070176.004105. [DOI] [PubMed] [Google Scholar]
- Roe B. A. Studies on human tRNA. I. The rapid, large scale isolation and partial fractionation of placenta and liver tRNA. Nucleic Acids Res. 1975 Jan;2(1):21–42. doi: 10.1093/nar/2.1.21. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schmidt O., Mao J. I., Silverman S., Hovemann B., Söll D. Specific transcription of eukaryotic tRNA genes in Xenopus germinal vesicle extracts. Proc Natl Acad Sci U S A. 1978 Oct;75(10):4819–4823. doi: 10.1073/pnas.75.10.4819. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Silberklang M., Gillum A. M., RajBhandary U. L. The use of nuclease P1 in sequence analysis of end group labeled RNA. Nucleic Acids Res. 1977 Dec;4(12):4091–4108. doi: 10.1093/nar/4.12.4091. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Simsek M., RajBhandary U. L. The primary structure of yeast initiator transfer ribonucleic acid. Biochem Biophys Res Commun. 1972 Oct 17;49(2):508–515. doi: 10.1016/0006-291x(72)90440-8. [DOI] [PubMed] [Google Scholar]
- White B. N., Tener G. M., Holden J., Suzuki D. T. Analysis of tRNAs during the development of Drosophila. Dev Biol. 1973 Jul;33(1):185–195. doi: 10.1016/0012-1606(73)90173-5. [DOI] [PubMed] [Google Scholar]