Table I.

Structural Statistics for KAP25 peptide: a) bound to SPase I Δ2-75 and b) in presence of DPC micelles

Parameter	Ensemble
Distance restraints	Bound a	DPCb
All	207		246
Short range (|i-j|<=1)	185	162
Medium-range (1<|i-j|<5)	22	74
Long-range (|i-j|>=5)	0	10
Average CYANA target function value	0.16	0.15
Violations
NOE (> 0.2 Å)	0	0
RMSDc
Average backbone RMSD to mean	1.48 Å	0.64 Å
Average heavy atom RMSD to mean	1.96 Å	0.96 Å
RMS Z score
Bond length	1.065+/- 0.000	1.065+/- 0.000
Bond angles	0.175+/- 0.001	0.174+/- 0.001
Omega angle restraints	0.019+/- 0.005	0.017+/- 0.007
Side chain planarity	0.029+/- 0.007	0.028+/- 0.006
Improper dihedral distribution	0.304+/- 0.002	0.304+/- 0.001
Ramchandran statisticsd
Residues in most favored regions	64.0%	62.9%
Residues in additional allowed regions	35.4%	37.1%
Residues in generously allowed regions	0.6%	0%
Residues in disallowed regions	0%	0%

^a20 mM Sodium phosphate buffer, 22 °C

^b20 mM Sodium phosphate buffer, 40 °C, 75mM DPC (1:1.4 peptide:micelles molar ratio)

^cResidues -11 to -1

^dAll residues