Figure 5.
Concentration response for desensitization by nicotine. Panel 5a shows data for [3H] GABA release from CX (n=10) and thalamus (n=6) of WT mice, as well as cortex of α5KO mice (n=7). Panel 5b shows data for [3H]-DA release from striatum of α6KO mice (n=4) and α5KO mice (n=5) in the presence of α-CtxMII (50 nM). Panel 5c presents data for [3H]-DA release from striatum of α4KO mice (n=5).