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. 1979 Jun 25;6(8):2697–2705. doi: 10.1093/nar/6.8.2697

Entrapment of plasmid DNA in liposomes.

G J Dimitriadis
PMCID: PMC327886  PMID: 379828

Abstract

The entrapment of plasmid DNA (pMB9) and high molecular weight DNA into large unilamellar liposomes is described. The entrapment of DNA is specific and due to encapsulation of DNA into the aqueous compartment of liposomes. The entrapped Dna, resistant to deoxyribonuclease treatment, could be reisolated from liposomes intact and, as has been shown by transformation assay, it remains biologically active. The advantages of our method and possible applications are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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