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. 1979 Jul 25;6(10):3399–3410. doi: 10.1093/nar/6.10.3399

Identification of a DNA polymerase β-like form in Drosophila melanogaster adult flies

Maria Furia 1, Lino C Polito 2, Giovanni Locorotondo 3, Pasquale Grippo 3
PMCID: PMC327941  PMID: 113777

Abstract

DNA polymerase β is widely distributed in the eukariotes. So far, few examples are known in which a DNA polymerase α -like form alone is reported. Surprisingly, DNA polymerase β was not detected in Drosophila embryos, while it is present in the cells of multicellular species from sponge to mammals. In view of the relevance of Drosophila as a model biological system for studying the role of the various DNA metabolism enzymes in vivo we have reinvestigated the presence of the DNA polymerase β-like form in Drosophila adult flies.

Here we report the occurrence in Drosophila melanogaster adult flies of a DNA polymerase activity that, for its NEM1 resistance, template specificity, sensitivity to ddTTP, sedimentation coefficient and nuclear localization can be classified as a β-like form.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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