Table 1.
Variable | Control diet | High-fat diet |
---|---|---|
Experiment 1 | ||
Body weight (g) | 33.20 ± 1.11 | 48.64 ± 0.94a |
Blood glucose (mmol/liter) | 8.48 ± 0.27 | 9.35 ± 0.41 |
Urination (ml) | 0.60 ± 0.11 | 1.61 ± 0.23a |
Urinary albumin excretion (μg per 24 h) | 13.68 ± 3.17 | 37.40 ± 4.61a |
Total kidney weight (g) | 0.374 ± 0.011 | 0.413 ± 0.008a |
Glomerular volume (μm3) | 253,122 ± 5,782 | 303,688 ± 13,528a |
Experiment 2 | ||
Body weight (g) | 30.3 ± 1.05 | 42.6 ± 0.72a |
Blood glucose (mmol/liter) | 7.54 ± 0.28 | 8.47 ± 0.61 |
Daily food consumption (g) | 3.48 ± 0.06 | 3.41 ± 0.12 |
Daily calorie intake (kcal) | 14.16 ± 0.25 | 18.93 ± 0.65a |
Data are expressed as means ± sem and n = 10–14 per group in experiment 1 and n = 14–15 per group in experiment 2.
P < 0.01 vs. mice fed the control diet.