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. 1991 Jun 25;19(12):3269–3274. doi: 10.1093/nar/19.12.3269

Two hypervariable minisatellite DNA binding proteins.

W P Wahls 1, G Swenson 1, P D Moore 1
PMCID: PMC328321  PMID: 2062643

Abstract

Hypervariable minisatellite DNA sequences are short, tandemly repeated sequences present at numerous loci in eukaryotes. They stimulate intermolecular homologous recombination up to 13-fold in human cells in culture and may be specific sites for the initiation of recombination in the eukaryotic genome (Wahls, W.P., Wallace, L.J., & Moore, P.D. (1990) Cell 60, 95-103). Reported here is the detection and partial purification of two hypervariable minisatellite DNA binding proteins, called Msbp-2 and Msbp-3, present in the nuclear extracts of human HeLa cells. The proteins elute from a gel filtration column with a native mass of 200-250 kDa and have sizes of 77 kDa and 115 kDa respectively.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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