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. 1991 Jul 11;19(13):3549–3551. doi: 10.1093/nar/19.13.3549

Curved DNA without AA/TT dinucleotide step.

I Brukner 1, V Jurukovski 1, M Konstantinović 1, A Savić 1
PMCID: PMC328378  PMID: 1852605

Abstract

The evidence is accumulating that dinucleotide steps other than AA/TT affect DNA flexure of AnTm (m + n greater than = 4) containing fragments. However, it is not clear whether macroscopic DNA flexure without AA/TT steps might occur. In this paper we demonstrate the anomaly in electrophoretic mobility of non AA/TT repetitive DNA sequences which is a function of sequence phasing. Therefore, our results show that PyPu (TA) and AG/CT steps, angulary separated by close to 180 degrees from Pu/Py (GC) and GG/CC steps, bend DNA, even in the absence of AnTm tracts.

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Selected References

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