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. Author manuscript; available in PMC: 2012 Nov 8.
Published in final edited form as: Biochemistry. 2011 Oct 18;50(44):9545–9550. doi: 10.1021/bi201055c

Figure 2.

Figure 2

X-ray crystal structure of reduced amide 2 (yellow) in complex with Pin1 at 1.76 Å. Left: The structure of reduced amide (SN)-2 (yellow) bound to Pin1 is shown as SIGMAA-weighted 2Fo - Fc electron-density map (blue) contoured at 1σ. Right: Prolyl nitrogen (RN)-epimer of 2 (turquoise) flexibly superimposed on the (SN)-epimer structure (yellow). Only the (SN)-epimer fit the electron density. (Created with MacPyMOL 2006.(41))