Table 2.
Involvement of S100 alarmins in inflammatory diseases
| Disease | Protective | Pathological | Reference | |
|---|---|---|---|---|
| Tumors | Skin/epidermal carcinomas | √ | [90, 91] | |
| Squamous cell carcinomas | √ | √ | [107, 108] | |
| Pterygium (benign conjunctiva growth) |
√ | [116, 117] | ||
| Liver carcinomas | √ | [118] | ||
| Infections | Vaginal candidiasis | √ | [71] | |
| Oral candidiasis | √ | [95] | ||
| HIV | √ | [88, 119] | ||
| Mycobacteriosis | √ | [120] | ||
| Streptococcal pneumonia | √ | [111] | ||
| Urinary tract infection (Ureaplasma) |
√ | [121] | ||
| Autoimmunity | Psoriasis | √ | [122] | |
| Rheumatoid arthritis | √ | [97, 98] | ||
| Cystic fibrosis | √ | [123, 124] | ||
| Chronic inflammatory bowel disease |
√ | [82, 105] | ||
| Sjogren’s syndrome | √ | [125] | ||
| Systemic lupus erythematosus |
√ | [126] | ||
| Others | Atherosclerosis | √ | [127, 128] | |
| Gouty arthritis | √ | [129] | ||
| Meibomian gland disease (an eyelid cyct) |
√ | [130] |