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. 2010;18(3):211–220.

Figure 4.

Figure 4

Effect of the type of cross-linking agent on drug release from zinc pectinate gel microparticles and calcium pectinate gel microparticles in simulated GI fluids. Preparation conditions: low methoxy-pectin concentration 4% w/v+cross-linking solution of pH 1.6+cross-linking time of 24 hrs+cross-linking agent Zn(CH3COO)2 [○]/CaCl2 [◊], Free drug [II] (A). Effect of rat caecal content on drug release from zinc pectinate gel microparticles and calcium pectinate gel microparticles in simulated colonic fluid (pH 6.8). Preparation conditions: low methoxy-pectin concentration 4% w/v+cross-linking solution pH 1.6+cross-linking time 24 hrs+cross- linking agent Zn(CH3COO)2 [○]/CaCl2 [◊], (B). Values are mean±s.d. (n=3).