Figure 1. Rejection and acceptance of vascualrized composite allografts in dogs.
Rejection of a vascularized composite allograft in a marrow donor dog (G499), showing early (day 18, A) and late (day 21, B) signs of rejection, with edema, erythema, and skin necrosis. In contrast, the graft in the mixed chimeric dog (G500) shown here on day 346 with normal hair growth (brown) and no evidence of edema or erythema (C).