Table 2.

Patient Outcomes (N = 41)

Outcome	Frequency/Estimate
Response ratea	5% (95% CI, 1–17)
No. of responders (PR)	2
Time to response, median mo	2.7 mo (range, 2–4)
Overall survival, median mob	7.6 mo (95% CI, 6.1–15.9)
6 months	66% (95% CI, 53–82)
12 months	39% (95% CI, 27–57)
18 months	34% (95% CI, 22–52)
Time to disease progression, median mob	2.0 (95% CI, 1.8–3.5)
2 months	54% (95% CI, 41–72)
3 months	41% (95% CI, 28–60)
4 months	22% (95% CI, 12–40)
6 months	13% (95% CI, 6–31)

CI indicates confidence interval; PR, partial response.

^an = 40; response sustained for at least 2 consecutive evaluations.

^bKaplan-Meier method.