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. Author manuscript; available in PMC: 2013 Jun 5.
Published in final edited form as: Virology. 2012 Mar 9;427(2):127–134. doi: 10.1016/j.virol.2012.02.010

Figure 3.

Figure 3

Phenotype of T329A DENV-1 in AG129 mice. A–C. AG129 mice were infected via an intracranial route with (A) 101, (B) 102, or (C) 103 PFU of wild type or T329A West-Pac-74 DENV-1 and followed for survival. The number of animals for each dose ranged from 5 to 6 per group. No differences were statistically significant. D. AG129 mice were untreated or pre-treated with 500 µg of DENV1-E106 prior to infection with wild type or T329A West-Pac-74 DENV-1. The number of animals for each antibody ranged from 10 to 18 per group. Statistically significant differences are described in the text.