. Author manuscript; available in PMC: 2012 Mar 27.

Published in final edited form as: Diabetes. 2001 Feb;50(2):322–328. doi: 10.2337/diabetes.50.2.322

TABLE 2.

AIRs to glucose and tolbutamide in children with congenital hyperinsulinism

Subject group	n	Baseline plasma insulin concentration (μU/ml)	Peak blood glucose concentration (mg/dl)	AIR to glucose (μU/ml)	Glucose disposal rate (%/min)	AIR to tolbutamide (μU/ml)
Diffuse SUR1^−/− hyperinsulinism	8	11 ± 2 (NS^*)	293 ± 17 (NS)	14 ± 4 (<0.05)	2 ± 0.3 (NS)	0.7 ± 1 (<0.005)
SUR1^+/− carriers	6	10 ± 2 (NS)	198 ± 12 (NS)	37 ± 13 (NS)	2 ± 0.2 (NS)	31 ± 8 (NS)
Normal adults	10	8 ± 1	262 ± 16	42 ± 9	2 ± 0.5	53 ± 12

Data are means ± SE (P) or means ± SE.

Significance values are presented for the difference between each group and the normal adults.