Table 2.

Cost-effectiveness results for pre-adolescent girls.^*

	Kenya†	Mozambique†	Tanzania†	Uganda†
	I$/YLS	I$/YLS	I$/YLS	I$/YLS
Adolescent vaccination followed by a single lifetime HPV DNA testing at age 35 (1-visit)‡
Cost per vaccinated girl: I$5 (I$0.55 per dose)
Vaccine	160	80	CS	20
Screening with HPV, age 35	§	§	§	§
Vaccine + screening with HPV, age 35	2090	1260	740	1000
Cost per vaccinated girl: I$10 (I$2.00 per dose)
Vaccine	470	250	90	130
Screening with HPV, age 35	§	§	§	§
Vaccine + screening with HPV, age 35	2090	1260	740	1000
Cost per vaccinated girl: I$25 (I$5.00 per dose)
Screening with HPV, age 35	1400	§	§	§
Vaccine	1440	750	440	490
Vaccine + screening with HPV, age 35	2090	1260	740	1000
Cost per vaccinated girl: I$50 (I$12.25 per dose)
Screening with HPV, age 35	1400	770	450	570
Vaccine	§	§	§	§
Vaccine + screening with HPV, age 35	3580	1870	1260	1300
Cost per vaccinated girl: I$200 (I$54.25 per dose)
Screening with HPV, age 35	1400	770	450	570
Vaccine	§	§	§	§
Vaccine + screening with HPV, age 35	15,000	7850	5610	5610
Adolescent vaccination followed by a single lifetime HPV DNA testing at age 35 (2-visit)‡
Cost per vaccinated girl: I$5 (I$0.55 per dose)
Vaccine	160	80	CS	20
Screening with HPV, age 35	§	§	§	§
Vaccine + screening with HPV, age 35	2810	1690	1060	1370
Cost per vaccinated girl: I$10 (I$2.00 per dose)
Vaccine	470	250	90	130
Screening with HPV, age 35	§	§	§	§
Vaccine + screening with HPV, age 35	2810	1690	1060	1370
Cost per vaccinated girl: I$25 (I$5.00 per dose)
Screening with HPV, age 35	§	§	§	§
Vaccine	1420	750	440	490
Vaccine + screening with HPV, age 35	2810	1690	1060	1370
Cost per vaccinated girl: I$50 (I$12.25 per dose)
Screening with HPV, age 35	1860	1010	630	770
Vaccine	§	§	§	1240
Vaccine + screening with HPV, age 35	3480	1830	1220	1370
Cost per vaccinated girl: I$200 (I$54.25 per dose)
Screening with HPV, age 35	1860	1010	630	770
Vaccine	§	§	§	§
Vaccine + screening with HPV, age 35	14,570	7650	5420	5450

^*YLS = years of life saved; HPV = human papillomavirus DNA testing; CS = cost-saving. All currencies are reported in 2005 international dollars (I$).

^†Gross domestic product (GDP) per capita, 2005 I$ for each country is as follows: Kenya (I$1470); Mozambique (I$791); Tanzania (I$1167); Uganda (I$1077).²⁸

^‡Analyses assume either 1-visit HPV testing or 2-visit HPV testing. The results should be interpreted assuming that a country has already decided to utilize a 1-visit or 2-visit strategy. Analyses that rely on alternative assumptions are provided in the Appendix.

^§These strategies are either more costly and less effective, or have higher incremental cost-effectiveness ratios than more effective options, and are thus considered dominated.